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Table 2 The association between the TBX21 rs41515744 polymorphism and LOAD (late-onset Alzheimer’s disease). P-values and ORs for the association are shown in dominant, codominant, and recessive models

From: TBX21, the Master regulator of the type 1 immune response, overexpresses in the leukocytes of peripheral blood in patients with late-onset Alzheimer’s disease

Group

Genotype (%)

Allele (%)

Dominant model

Co-dominant model

Recessives model

CC

CT

TT

C

T

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Case

155 (79.8)

33 (17)

6 (3.1)

343 (88.4)

45 (11.6)

1.94 (1.11–3.39)

0.019

1.58 (1–2.48)

0.044

1.24 (0.37–4.15)

0.72

Control

177 (88.5)

18 (9)

5 (2.5)

372 (90.5)

28 (9.5)

  1. The number of subjects with each genotype and number of alleles (frequency in %)
  2. ORs for different modes of inheritance were calculated using the Web-Assotest program
  3. OR Odds ratio, CI Confidence interval
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Immunity & Ageing

ISSN: 1742-4933

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