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Table 3 Summary of P-values and ORs for the association between TBX21 rs17244587 and LOAD in dominant, codominant, and recessive models

From: TBX21, the Master regulator of the type 1 immune response, overexpresses in the leukocytes of peripheral blood in patients with late-onset Alzheimer’s disease

Group

Genotype (%)

Allele (%)

Dominant model

Co-dominant model

Recessives model

GG

GA

AA

G

A

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Case

178 (91.8)

6 (3.1)

10 (5.1)

362 (93.3)

26 (6.7)

0.73 (0.37–1.43)

0.35

0.89 (0.59–1.35)

0.59

1.03 (0.42–2.54)

0.94

Control

178 (89)

12 (6)

10 (5)

368 (92)

32 (8)

  1. The number of subjects with each genotype and number of alleles (frequency in %)
  2. OR Odds ratio, CI Confidence interval, LOAD Late-onset Alzheimer’s disease
  3. ORs for different modes of inheritance were calculated using the Web-Assotest program
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Immunity & Ageing

ISSN: 1742-4933

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