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Correction: Heat‑killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans

The Original Article was published on 02 August 2024

Correction: Immun Ageing 21, 52 (2024)

https://doi.org/10.1186/s12979-024-00457-w


Following publication of the original article [1], the authors identified an error in Fig. 1. The legend of graph I in Fig. 1 was missing. The correct figure is given below.

Incorrect: Fig. 1

Fig. 1
figure a

Feeding of probiotic heat-killed MKAK9 improves longevity, age-associated biomarkers and resistance of worms against pathogenic infections and abiotic stress in worms. A A lifespan assay on worms was performed after feeding with the bacteria: heat-killed E. coli OP50 (HK OP50), E. coli OP50 (OP50), heat-killed L. brevis MKAK9 (HK MKAK9), L. brevis MKAK9 (MKAK9), and (***P < 0.0001, log-rank test). B-C The pharynx pumps, and locomotory activity of heat-killed bacterium-treated worms were measured on day 14. D-E The accumulation of the aging pigment lipofuscin was measured on day 14 in heat-killed bacterium-treated worms. The lipofuscin levels were observed in worms under a confocal microscope (10X magnification, scale bar, 100 μm). F-G Treatment of HK MKAK9 increased the mean survival of worms against oxidative stress (Paraquat, 10 mM) and heat stress at 35 °C. H-I Pre-treatment of worms on HK reduced the colonization of pathogens S. aureus MTCC 3160 and E. coli MTCC 1687 in the intestine of worms. The heat-killed bacterium-treated effects were statistically compared using a Student’s t-test (*P < 0.05 and **P < 0.01). The error bars represent the mean ± SEM

Correct: Fig. 1

Fig. 1
figure b

Feeding of probiotic heat-killed MKAK9 improves longevity, age-associated biomarkers and resistance of worms against pathogenic infections and abiotic stress in worms. A A lifespan assay on worms was performed after feeding with the bacteria: heat-killed E. coli OP50 (HK OP50), E. coli OP50 (OP50), heat-killed L. brevis MKAK9 (HK MKAK9), L. brevis MKAK9 (MKAK9), and (***P < 0.0001, log-rank test). B-C The pharynx pumps, and locomotory activity of heat-killed bacterium-treated worms were measured on day 14. D-E The accumulation of the aging pigment lipofuscin was measured on day 14 in heat-killed bacterium-treated worms. The lipofuscin levels were observed in worms under a confocal microscope (10X magnification, scale bar, 100 μm). F-G Treatment of HK MKAK9 increased the mean survival of worms against oxidative stress (Paraquat, 10 mM) and heat stress at 35 °C. H-I Pre-treatment of worms on HK reduced the colonization of pathogens S. aureus MTCC 3160 and E. coli MTCC 1687 in the intestine of worms. The heat-killed bacterium-treated effects were statistically compared using a Student’s t-test (*P < 0.05 and **P < 0.01). The error bars represent the mean ± SEM

The original article [1] has been updated.

Reference

  1. Kumar A, Saha MK, Kumar V, et al. Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans. Immun Ageing. 2024;21:52. https://doi.org/10.1186/s12979-024-00457-w.

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Correspondence to Mojibur R. Khan.

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Kumar, A., Saha, M.K., Kumar, V. et al. Correction: Heat‑killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans. Immun Ageing 21, 58 (2024). https://doi.org/10.1186/s12979-024-00464-x

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  • DOI: https://doi.org/10.1186/s12979-024-00464-x